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Get Cardiovascular Drug Therapy: Nitrate Therapy PDF

By Adam Schneeweiss

ISBN-10: 3540509623

ISBN-13: 9783540509622

ISBN-10: 3642746179

ISBN-13: 9783642746178

The· first assembly of the cardiovascular drug remedy discussion board happened on April 13-15, 1988 in Montreux, Switzerland. during this assembly, which was once closed to the general public, nearly a hundred and fifty prime investigators within the box of cardiovascular drug treatment, either lecturers and from the pharmaceutical undefined, mentioned the cutting-edge and destiny tendencies of this swiftly increasing box. The discussions focused on 4 significant themes: (1) ischemic center illness; (2) middle failure; (3) hyper­ rigidity; (4) arrhythmias. those issues have been mentioned via 4 committees in parallel, and thereafter the details have been reviewed via the full discussion board. This framework allowed either in depth and interdisciplinary discussions. This ebook, the 1st book of chosen issues from the assembly, focuses mostly on nitrate treatment in ischemic middle ailment and center failure. Adam Schneeweiss, MD Chairman v Contents starting comments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Presentation of the Sir Thomas Lauder Brunton Award for awesome Nitrate examine . . . . . . . . . . . . . . . . . . . . . . . . . . three Origins of indicators in center Failure - Relevance in evaluate of latest medicinal drugs . . . . . . . . . . . . . . . . . . . . five Mononitrates in Congestive center Failure . . . . . . . . . . . . . . . . . nine Are There adjustments among a number of the Formulations of Nitrates in center Failure? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . eleven long term Nitrate treatment - A Decade of fixing thoughts . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Nitrate treatment in Angina Pectoris . . . . . . . . . . . . . . . . . . . . . . . . 23 Mononitrates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Transdermal management of Nitrates . . . . . . . . . . . . . . . . . . . fifty three Nitrates in Angina Pectoris - reason of Use and Avoidance of boundaries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . sixty seven remedy of Congestive center Failure - precis . . . . . . . .

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Extra info for Cardiovascular Drug Therapy: Nitrate Therapy

Example text

Eggeling et al. [4] studied the effect of slow-release IS-5-MN, 50 mg once daily, in eight patients with severe cor40 onary artery disease. Exercise stress tests were performed before treatment, on placebo and on the active drug, at 1, 2, 4, 8, and 24 h after administration. Maximal work load increased significantly at 1-8 h after administration of IS-5-MN but returned to pretreatment level after 24 h. Akhras and Jackson [5] studied the anti anginal efficacy of monotherapy with IS-5-MN in 14 patients with coronary artery disease and chronic stable angina pectoris.

This agent did not produce hemodynamic tolerance. Muller et al. d. The response of heart rate to IS-5-MN is variable. In most studies heart rate was not altered or was slightly increased. However, in some cases (mainly those with congestive heart failure), decreases in heart rate have been observed. Comparative Studies of Mononitrates and Other Drugs in Angina Pectoris Calcium Antagonists Both calcium antagonists and nitrates reduce preload and afterload, thereby reducing myocardial oxygen consumption.

In: Borchard U, Raffienbeul W, Schrey A (eds) Mononitrat. Universitatsdruckerei und Wolf, Munich, pp 176--183 Ohlmeier H, Mertens HM, Mannebach H, Gleichmann U (1985) Tolerance and rebound phenomena in nitrate therapy. In: Cohn JH, Rittinghausen R (eds) Mononitrates. Springer, Berlin Heidelberg New York, pp 107-123 Eggeling T, Osterspey A, Geppert R, Jansen W (1985) Antianginose Wirksamkeit von retardiertem Isosorbid-5-Mononitrat bei Patienten mit koronarer Herzkrankheit. In: Borchard U, Raffienbeul W, Schrey A (eds) Mononitrat.

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Cardiovascular Drug Therapy: Nitrate Therapy by Adam Schneeweiss


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