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Read e-book online Basis and Treatment of Cardiac Arrhythmias PDF

By Robert E. Kass, Colleen E. Clancy

ISBN-10: 3540249672

ISBN-13: 9783540249672

This ebook contains the main up-to date info with regards to mechanisms and remedy of cardiac arrhythmia. a few of the issues mentioned during this textual content replicate very lately undertaken study instructions together with genetics of arrhythmias, mobilephone signalling molecules as capability healing objectives and trafficking to the membrane. those new techniques and implementations of anti-arrhythmic treatment derive from many many years of analysis as defined within the first bankruptcy by way of individual Professors Michael Rosen (Columbia college) and Michiel Janse (University of Amsterdam). The textual content covers alterations in methods to treatment through the years, arrhythmias in a number of cardiac areas and over many scales, from gene to protein to phone to tissue to organ.

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Extra resources for Basis and Treatment of Cardiac Arrhythmias

Example text

J Physiol (Lond) 8:296–310 McWilliam JA (1887b) On electrical stimulation of the heart. Trans Int Med Congress, 9th session, Washington, vol III, p 253 McWilliam JA (1889) Cardiac failure and sudden death. Br Med J 1:6–8 Miles WM, Zipes DP (2000) Atrioventricular reentry and variants: mechanisms, clinical features and management. In: Zipes, Jalife J (eds) Cardiac electrophysiology: from cell to bedside, third edn. WB Saunders, Philadelphia, pp 488–504 Mines GR (1913a) On functional analysis by the action of electrolytes.

3 Role of I f in Generating Cardiac Rhythms and Arrhythmias Animal Models . . . . . . . . . . . . . Human Disease . . . . . . . . . . . . HCN as a Biological Pacemaker . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60 60 61 62 5 Conclusions . . . . . . . . . . . . . . . . . . 63 References . . . . . . . . . . . . . . . . . . . . 64 . . . . . . . . . . Abstract The ionic basis of automaticity in the sinoatrial node and His–Purkinje system, the primary and secondary cardiac pacemaking regions, is discussed.

4 The Pacemaker Current I f . . . . . . . Biophysical Description . . . . . . . . Molecular Description . . . . . . . . Regional Distribution of HCN Isoforms and MiRP1 Approaches for Region-Specific Modification of I f . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Role of I f in Generating Cardiac Rhythms and Arrhythmias Animal Models . . . . . . . . . . . . . Human Disease . . . . . . . . . . .

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Basis and Treatment of Cardiac Arrhythmias by Robert E. Kass, Colleen E. Clancy


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