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Read e-book online Arteriosclerosis - A Medical Dictionary, Bibliography, and PDF

By Icon Health Publications

ISBN-10: 0597843384

ISBN-13: 9780597843389

ISBN-10: 141751258X

ISBN-13: 9781417512584

It is a 3-in-1 reference booklet. It provides a whole scientific dictionary overlaying 1000s of phrases and expressions when it comes to arteriosclerosis. It additionally provides large lists of bibliographic citations. eventually, it presents details to clients on tips on how to replace their wisdom utilizing numerous web assets. The publication is designed for physicians, scientific scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to familiarize yourself with examine devoted to arteriosclerosis. in case your time is effective, this e-book is for you. First, you won't waste time looking out the net whereas lacking loads of appropriate details. moment, the ebook additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing countless numbers of websites.

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Extra info for Arteriosclerosis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

Example text

First, the PI will test whether infusion of anti-IL-4 mAb of rIFNg/rIL-2 may prevent tolerance induction, and recreate cardiac Tx rejection in test recipients. He also proposes to use in vivo gene transfers utilizing IL-4 and IFN-g encoding replication-deficient adenoviral vectors. He will determine whether intra-Tx overexpression of IL-4 may boost the Th2-type milieu, and amplify the IT pathway. He will assess how cytokine gene transfer affects intra-Tx cellular infiltrate/activation and Th1/Th2 cytokine expression profile.

Studies will also address new approaches for gene delivery of multiple genes together by using helper-dependent adenovirus vector in vivo to evaluate the synergistic effect of this strategy on the treatment for hyperlipidemia. Taken together, these studies will provide understanding of target(s) underlying predisposition to atherogenesis. The study will shed new insights to the understanding of the structure/function of the apoB mRNA hammerhead ribozyme, and the possible application of using this ribozyme as a therapeutic agent for the treatment of atherosclerosis.

Thus, a biochemical mechanism unique to Hcy remains to be identified. We have proposed hypomethylation as a specific mechanism by which Hcy induces vascular injury and leads to cardiovascular disease. The basic hypothesis of the ongoing and this proposed projects is that Hcy, at clinically relevant concentrations, selectively inhibits EC growth through a hypomethylation-related mechanism. The ongoing research is designed to investigate the role of Ras demethylation in Hcy-EC growth, to dissect the mechanism in Hcy signaling using cellular and animal models.

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Arteriosclerosis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications


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